WEI LAB

Cancer Bioinformatics for Precision Medicine

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Wei Lab Publications

For further information, consult Google Scholar or PubMed.

Selected Publications (* co-first author; # co-corresponding author)

1. Chow, L. K. Y.*, Lai-Shun Chung*, D., Tao, L., Chan, K. F., Tung, S. Y., Cheong Ngan, R. K., Ng, W.T., Wing-Mui Lee, A., Yau, C. C., Lai-Wan Kwong, D., Ho-Fun Lee, V., Lam, K. O., Liu, J., Chen, H., Dai, W#. & Lung, M. L#. Epigenomic landscape study reveals molecular subtypes and EBV-associated regulatory epigenome reprogramming in nasopharyngeal carcinoma. EBioMedicine 86, 104357 (2022). (IF=11.2)

2. Islam KA, Chow LK, Kam NW, Wang Y, Chiang CL, Choi HC, Xia YF, Lee AW, Ng WT#, Dai W#. Prognostic Biomarkers for Survival in Nasopharyngeal Carcinoma: A Systematic Review of the Literature. Cancers (Basel). 2022 Apr 24;14(9):2122. doi: 10.3390/cancers14092122. (IF=6.64)

3. Dai W#, Chung DLS, Chow LKY, Yu VZ, Lei LC, Leong MML, Chan CKC, Ko JMY, and Lung ML#. Clinical Outcome-Related Mutational Signatures Identified by Integrative Genomic Analysis in Nasopharyngeal Carcinoma. Clin Cancer Res. 2020; 26(24). (IF=10.107)

4. Gong L, Kwong D, Dai W, Wu P, Li S, Yan Q, Zhang Y, Zhang B, Fang X, Liu L, Luo M, Liu B, Chow LKY, Chen Q, Huang J, Lee VH, Lam KO, Lo AWI, Chen Z, Wang Y, Lee A, and Guan XY. Comprehensive single-cell sequencing reveals the stromal dynamics and tumor-specific characteristics in the microenvironment of nasopharyngeal carcinoma. Nat Commun. 2021; 12(1). (IF=12.121)

5. Leong MML, Cheung AKL, Dai W, Tsao SW, Tsang CM, Dawson WD, Ko JMY, Lung ML. Epstein-Barr virus modulates a histone bivalent switch to suppress DNA damage repair pathway expression in squamous epithelial cells. Proc Natl Acad Sci U S A. 2019, 116(28):14144-14153. (IF=9.412)

6. Lin W, Yip YL, Jia L, Deng W, Zheng H, Dai W, Ko JM, Chung GTY, Yip KY, Lee SD, Kwang SH, Zhang J, Liu T, Chan JYW, Kwong DLW, Lee VHF, Nicholls JM, Busson P, Liu X, Chiang AK, Hui KF, Kwok H, T. CS, Cheung YC, Chan CK, Li B, Cheung ALM, Hau PM, Zhou Y, Tsang CM, Middeldorp J, Chen H, Lung ML, Tsao SW: Establishment and characterization of new tumor xenografts and cancer cell lines from EBV-positive nasopharyngeal carcinoma. Nat Commun 2018, 9(1):4663. (IF=12.121)

7. Dai W, Ko JMY, Choi SSA, Yu Z, Ning L, Zheng H, Gopalan V, Chan KT, Lee NP, Chan KW, Law SY, Lam AK, Lung ML: Whole-exome sequencing reveals critical genes underlying metastasis in oesophageal squamous cell carcinoma. J Pathol 2017, 242(4):500-510. (IF=6.021)

8. Chatterjee J*, Dai W*, Aziz NHA, Teo PY, Wahba J, Phelps DL, Maine CJ, Whilding LM, Dina R, Trevisan G, Flower KJ, George AJT, Ghaem-Maghami S: Clinical Use of Programmed Cell Death-1 and Its Ligand Expression as Discriminatory and Predictive Markers in Ovarian Cancer. Clin Cancer Res 2017, 23(13):3453-3460. (IF=10.107)

9. Zheng H*, Dai W*, Cheung AK*, Ko JM, Kan R, Wong BW, Leong MM, Deng M, Kwok TC, Chan JY, Kwong DL, Lee AW, Ng WT, Ngan RK, Yau CC, Tung S, Lee VH, Lam KO, Kwan CK, Li WS, Yau S, Chan KW, Lung ML: Whole-exome sequencing identifies multiple loss-of-function mutations of NF-kappaB pathway regulators in nasopharyngeal carcinoma. Proc Natl Acad Sci U S A 2016, 113(40):11283-11288. (IF=9.412)

10. Dai W*, Zheng H*, Cheung AK, Tang CS, Ko JM, Wong BW, Leong MM, Sham PC, Cheung F, Kwong DL, Ngan RK, Ng WT, Yau CC, Pan J, Peng X, Tung S, Zhang Z, Ji M, Chiang AK, Lee AW, Lee VH, Lam KO, Au KH, Cheng HC, Yiu HH, Lung ML: Whole-exome sequencing identifies MST1R as a genetic susceptibility gene in nasopharyngeal carcinoma. Proc Natl Acad Sci U S A 2016, 113(12):3317-3322. (IF=9.412)

11. Dai W, Zheng H, Cheung AK, Lung ML: Genetic and epigenetic landscape of nasopharyngeal carcinoma. Chin Clin Oncol 2016, 5(2):16.

12. Yu VZ, Wong VC, Dai W, Ko JM, Lam AK, Chan KW, Samant RS, Lung HL, Shuen WH, Law S, Chan YP, Lee NP, Tong DK, Law TT, Lee VH, Lung ML: Nuclear Localization of DNAJB6 Is Associated With Survival of Patients With Esophageal Cancer and Reduces AKT Signaling and Proliferation of Cancer Cells. Gastroenterology 2015, 149(7):1825-1836 e1825. (IF=17.373)